Tetrapyrroles and derivatives
Medchemexpress LLC Biliverdin | 114-25-0 | 70.0% | C33H34N4O6 | 10MG
Biliverdin is a green tetrapyrrolic bile pigment produced by heme catabolism, supplied as a research-grade reagent for biochemical and cell biology studies. It is commonly used as an endogenous metabolite in inflammation and heme metabolism research; handle protected from light and prepare DMSO stocks for in vitro work.
Chemscene ChemScene | (S)-3-hydroxydihydrofuran-2(3H)-one | 250MG | CS-0312594 | 0.97 | 52079-23-9| MFCD00211245 | 102.09
ChemScene | (S)-3-hydroxydihydrofuran-2(3H)-one | 250MG | CS-0312594 | 0.97 | 52079-23-9| MFCD00211245 | 102.09
Medchemexpress LLC Protoporphyrin IX (disodium) | 50865-01-5 | 96.5% | 25 MG
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway. It acts as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. This product is promising for research of sonodynamic and photodynamic agents for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Final intermediate in the heme biosynthetic pathway
- Acts as a radiation sensitizer
- Enhances ROS generation and induces DNA damage
- Functions as a photosensitizer
- Undergoes photobleaching by light irradiation
- Accumulates in tumor cells after 5-aminolevulinic acid administration
- Causes selective improvement of basal cell carcinoma
- Promising for research into sonodynamic and photodynamic agents for various cancers
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 500mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
eMolecules 14643-66-4 | Medchem Express | Coproporphyrin III | 1mg | 446256752 | HY-101398 | 654.72 | C36H38N4O8
Ambeed | (9-Oxo-9H-fluoren-2-yl)boronic acid | 250mg | 721299020 | A1618029 | 2036064-15-8 | 224.020 | C13H9BO3
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eMolecules 19444-84-9 | Ambeed | 3-Hydroxydihydrofuran-2(3H)-one | 1g | 525145111 | A237190 | MFCD00134268 | 102.089 | C4H6O3
Medchem Express | (Z)-Thiothixene | 5mg | 446259291 | HY-108324 | 3313-26-6 | MFCD00079574 | 443.620 | C23H29N3O2S2
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Enzo Life Sciences Protoporphyrin IX (free acid) (300mg). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
Cayman Chemical Mn III ProtoporphyrIn IX Chl
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Medchemexpress LLC Zinc protoporphyrin (Zn(II)-protoporphyrin IX) | 15442-64-5 | 99.9% | 626.02 g/mol | C34H32N4O4Zn | 1 ML
Zinc protoporphyrin (Zn(II)-protoporphyrin IX) is a research reagent that acts as a competitive heme oxygenase-1 (HO-1) inhibitor and a biomarker for iron-deficiency screening. It is supplied as a ready-to-use 10 mM solution in DMSO and as solid preparations for laboratory use. Typical applications include cellular assays, mechanistic studies, and in vivo screening.
- Ready-to-use 10 mM solution in DMSO.
- Also available as solid in multiple mass sizes.
- Competitive heme oxygenase-1 (HO-1) inhibitor for research.
- Used as a screening marker for iron deficiency in vivo.
- High purity (approximately 99.9%).
- Molecular weight 626.02 g/mol; formula C34H32N4O4Zn.
- Includes product data sheet and SDS for handling information.
![eMolecules 71216-20-1 | 2(3H)-Benzothiazolethione, 5-bromo- | Combi-Blocks, Inc. | MFCD01569939 | 246.140 | C7H4BrNS2 | 95.000 | Brc1ccc2sc(=S)[nH]c2c1 | 1g | 603140428](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502187689.JPG-250.jpg)
eMolecules 71216-20-1 | 2(3H)-Benzothiazolethione, 5-bromo- | Combi-Blocks, Inc. | MFCD01569939 | 246.140 | C7H4BrNS2 | 95.000 | Brc1ccc2sc(=S)[nH]c2c1 | 1g | 603140428
2(3H)-Benzothiazolethione, 5-bromo- | Combi-Blocks, Inc. | 71216-20-1 | MFCD01569939 | 246.140 | C7H4BrNS2 | 95.000 | Brc1ccc2sc(=S)[nH]c2c1 | 1g | 603140428
Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00078028 | ≥98.0% | 100 MG
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. It accumulates following 5-aminolevulinic acid (5-ALA) administration in rat tumor cells. When activated by red fluorescence at a peak wavelength of 405 nm, Protoporphyrin IX selectively improves basal cell carcinoma. It shows promise as a sonodynamic and photodynamic agent for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Acts as a radiation sensitizer enhancing ROS generation.
- Induces DNA damage.
- Acts as a photo sensitizer.
- Promising for research of sonodynamic and photodynamic agents for a wide range of cancers.
Medchemexpress LLC Chlorin e6 trisodium | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 5mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Frontier Specialty Chemicals 250MG MESO-TETRA(2,4,6-TRIMETH
meso-Tetra(2,4,6-trimethylphenyl)porphine; CAS: 56396-12-4; 250mg